Thiazolidinedione – wikipedia, The thiazolidinediones / θ aɪ. ə ˌ z oʊ l ɪ d iː n ˈ d aɪ. oʊ n /, abbreviated as tzd, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered c 3 ns ring..
Thiazolidinediones – mechanisms of action – australian, The thiazolidinediones (or ‘glitazones’) are a new class of drugs for the treatment of type 2 diabetes. they bind avidly to peroxisome proliferator-activated receptor gamma in adipocytes to promote adipogenesis and fatty acid uptake (in peripheral but not visceral fat). by reducing circulating fatty acid concentrations and lipid availability in liver and muscle, the drugs improve the patients sensitivity to insulin..
The mode of action of thiazolidinediones, Abstract. the thiazolidinediones (tzds) or ‘glitazones’ are a new class of oral antidiabetic drugs that improve metabolic control in patients with type 2 diabetes through the improvement of insulin sensitivity. tzds exert their antidiabetic effects through a mechanism that involves activation of the gamma isoform of the peroxisome proliferator-activated receptor (ppar gamma), a nuclear receptor..
Thiazolidinediones – an overview | sciencedirect topics, Thiazolidinediones thiazolidinediones (tzds) enhance glucose uptake and utilization in peripheral tissues, mainly skeletal muscle tissue. tzds bind to specific nuclear receptors called peroxisome proliferator activated receptor gamma (ppar-γ) that induce gene expression of proteins involved in the action at the post-insulin receptor level..
Thiazolidinediones – drugbank, Thiazolidinediones accession number dbcat002198 description. a group of oral anti-diabetic drugs designed to treat patients with type 2 diabetes. thiazolidenediones are compounds that act as agonists of the peroxisome proliferator-activated receptor-gamma increasing tissues sensibility (muscle, adiposity tissue, and liver) to insulin action..
List of thiazolidinediones (glitazones) – drugs.com, Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. they are a type of oral hypoglycemic (a medicine that lowers blood glucose levels). thiazolidinediones bind to a receptor called the peroxisome proliferator activated receptor-gamma in adipocytes (fat cells) and promote maturation of fat cells and deposition of fat into peripheral tissues..